Cat Benadryl Dosage Calculator

Calculate the correct Diphenhydramine dosage in liquid milliliters (mL) or tablet ftions for feline allergies and insect stings.

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Input Parameters

Enter cat weight and formulation.

Single Recommended Dose

10.0 mg
Liquid Volume: 4.0 mL
Dosing Frequency: Every 8 to 12 Hours
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Flavoring Tip

Diphenhydramine liquid is extremely bitter to felines. Mix liquid doses into a small spoon of wet food or tuna juice to avoid intense foaming at the mouth.

Cat Benadryl Dosage Reference Chart

Cat Weight (lbs / kg) Single Dose (mg) Liquid Dose (12.5mg/5mL) 25 mg Tablet Dose
5 lbs (2.3 kg) 5.0 mg 2.0 mL 1/4 Tablet
8 lbs (3.6 kg) 8.0 mg 3.2 mL 1/3 Tablet
10 lbs (4.5 kg) 10.0 mg 4.0 mL 1/2 Tablet
12 lbs (5.4 kg) 12.0 mg 4.8 mL 1/2 Tablet
15 lbs (6.8 kg) 15.0 mg 6.0 mL 1/2 to 3/4 Tablet

Calculation Methodology & Pharmacological Guidelines

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Veterinary Dosing Formula

Dose (mg) = Body Weight (lbs) × 1.0 mg/lb Liquid Volume (mL) = (Dose mg / 12.5 mg) × 5 mL

Diphenhydramine competes with histamine for H1-receptor sites on effector cells, relieving allergic itch and inflammation.

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Veterinary Disclaimer

Never give Benadryl formulations containing decongestants or alcohol. Always verify exact dosing with your veterinarian before treatment.

Frequently Asked Questions

What is the safe Benadryl dosage for cats?

The standard veterinary dosage of Benadryl (diphenhydramine) for cats is 1 mg per pound of body weight (approx 2 mg per kg), administered every 8 to 12 hours as directed by a veterinarian.

Which type of Benadryl is safe for cats?

Only use plain Diphenhydramine HCl (liquid children's Benadryl 12.5 mg / 5 mL or plain 25 mg tablets). NEVER use products containing decongestants (pseudoephedrine, phenylephrine), acetaminophen, or alcohol.

What are the common side effects of Benadryl in cats?

Common side effects include drowsiness, sedation, dry mouth, or paradoxically extreme agitation/hypetivity in some felines. Liquid Benadryl has a bitter taste that may cause foaming at the mouth.

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