MELD Score Calculator

Calculate the Model for End-Stage Liver Disease (MELD) score to predict mortality and transplant priority.

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Input Parameters

Enter details for calculation.

MELD Score

9
Low 3-Month Mortality Risk
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Expert Tip

MELD scores range from 6 to 40. Patients with scores ≥ 15 are generally placed on the liver transplant priority list.

Calculation Methodology & Details

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Formula

MELD = 3.78 × ln(Bili) + 11.2 × ln(INR) + 9.57 × ln(Creat) + 6.43

Calculates points using natural logs of liver and renal labs. Sodium correction is applied for values < 137.

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Important Disclaimer

The calculations provided are for educational and general informational purposes only. They do not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider.

How MELD is Calculated

Follow these steps to use this calculator:

1

Enter Lab Values

Input bilirubin, INR, serum creatinine, and sodium.

2

Read Priority Rating

Check standard 3-month survival statistics.

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Detailed Insights & Expert Guide

ℹ️ About this Calculation

This clinical oncology calculator provides chemotherapy dosing precision, tumor staging risk stratification, performance status scoring, and prognostic index evaluation based on ASCO and NCCN clinical guidelines.

Variable Glossary

Input

Oncology & Lab Data

Serum creatinine/eGFR, target AUC, GFR (Calvert formula), BSA (m²), tumor size/grade, or biopsy scores.

Parameter

Prognostic Index

Calculated dose (mg), ECOG grade (0-5), Nottingham Index score, or 10-year cancer risk percentage.

How to Calculate Step-by-Step

1

Step 1

Enter patient body surface area, GFR/creatinine clearance, or histopathological biopsy findings.

2

Step 2

Specify target AUC dose parameters or patient functional performance status options.

3

Step 3

Review calculated chemotherapy total mg dose, risk stratification category, or survival probability estimates.

FAQ

How is Carboplatin dose calculated using the Calvert formula?
The Calvert formula calculates Total Dose (mg) = Target AUC × (GFR + 25), where GFR is typically estimated using Cockcroft-Gault creatinine clearance capped at 125 mL/min.
What is the difference between ECOG and Karnofsky performance status?
ECOG ranges from 0 (fully active) to 5 (deceased), providing a 6-point scale. Karnofsky runs from 100% to 0% in 10-point increments. Both measure patient functional capacity in oncology clinical trials.
Can oncology calculators replace multidisciplinary tumor board review?
No. Chemotherapy dosing and oncologic risk modeling serve as clinical decision support. All treatment protocols require verification by a board-certified medical oncologist.